Professor Info
Group leader: Keihan Ghatreh samani
 
Group Name: Clinical Biochemistry & Nutrition
Affiliation: School of Medicine
 

Research Activities:
 
- Molecular genetics
- Gene expression
- Cardiovascular research
- Obesity

Selected Publications:
 
1. Farrokhi E, Ghatreh-Samani K, Salehi-Vanani N, Mahmoodi A. The resveratrol and expression of matrix metalloproteinase 9, and its tissue inhibitors in vascular smooth muscle cells. ARYA Atheroscler. 2018; 14(4): 157-162.
 
2. Mahmoudi A, Samani KG, Farrokhi E, Heidarian E. Effects of Nigella sativa Extracts on the Lipid Profile and Uncoupling Protein-1 Gene Expression in Brown Adipose Tissue of Mice. Advanced Biomedical Research.2018; 7 (1), 121.
 
3. Khaledifar A, Hashemzadeh M, Solati K, Poustchi H, Bollati V, Ahmadi A Kheiri S, Ghatreh samani K, Banitalebi M, Sedehi M, Malekzadeh R. The protocol of a population-based prospective cohort study in southwest of Iran to analyze common non-communicable diseases: Shahrekord cohort study. BMC Public Health. 2018; 18:660
 
4. Nejadtaghi, M., Jafari, H., Farrokhi, E., Samani, K.G. Familial Colorectal Cancer Type X (FCCTX) and the correlation with various genes—A systematic review
(2017) Current Problems in Cancer, 41 (6), pp. 388-397.
 
5. Heidarian, E., Jafari-Dehkordi, E., Valipour, P., Ghatreh-Samani, K., Ashrafi-Eshkaftaki, L. Nephroprotective and Anti-Inflammatory Effects of Pistacia atlantica Leaf Hydroethanolic Extract Against Gentamicin-Induced Nephrotoxicity in Rats (2017) Journal of Dietary Supplements, 14 (5), pp. 489-502.
 
6. Ranjbari, A., Heidarian, E., Ghatreh-Samani, K. Effects of thymoquinone on IL-6 gene expression and some cellular signaling pathways in prostate cancer PC3 cells
(2017) Jundishapur Journal of Natural Pharmaceutical Products, 12 (3), art. no. e63753.
 
7. Amini, S.-A., Ghatreh-Samani, K., Habibi-Kohi, A., Jafari, L. Comparison of pure palm olein oil, hydrogenated oil-containing palm, and canola on serum lipids and lipid oxidation rate in rats fed with these oils (2017) Archives of Iranian Medicine, 20 (2), pp. 96-100.
 
8.Yaghoobi, A., Ghatreh Samani, K., Amini, S.A., Gholami, M. Effects of cumin extract on serum lipid profile and total antioxidant capacity in rats receiving high-fat diet (2017) Journal of Zanjan University of Medical Sciences and Health Services, 25 (110), pp. 13-23.
 
9. Heidarian, E., Amini, S.A., Abbasi-Veldani, A., Ghatreh-Samani, K. Effects of quercetin on signaling proteins (PSTAT3, pERK1/2, pAKT) and interleukin-6 gene expression in prostate cancer pc3 cells (2017) Journal of Mazandaran University of Medical Sciences, 26 (144), pp. 290-300.
 
10. Heidarian, E., Keloushadi, M., Ghatreh-Samani, K., Valipour, P.The reduction of activity by gallic acid in prostate cancer PC3 cells (2016) Biomedicine and Pharmacotherapy, 84, pp. 264-269.
 
11. Keihan, G.S., Gharib, M.H., Momeni, A., Hemati, Z., Sedighin, R. A comparison between the effect of cuminum cyminum and vitamin E on the level of leptin, paraoxonase 1, HbA1c and oxidized LDL in diabetic patients (2016) International Journal of Molecular and Cellular Medicine, 5 (4), pp. 229-235.
 
12. Ghatreh-Samani, M., Esmaeili, N., Soleimani, M., Asadi-Samani, M., Ghatreh-Samani, K., Shirzad, H. Oxidative stress and age-related changes in T cells: Is thalassemia a model of accelerated immune system aging? (2016) Central European Journal of Immunology, 41 (1), pp. 116-124.
 
13. Farrokhi, E., Samani, K.G., Chaleshtori, M.H., Tabatabaiefar, M.A. Effect of oxidized low density lipoprotein on the expression of runx2 and SPARC genes in vascular smooth muscle cells (2015) Iranian Biomedical Journal, 19 (3), pp. 160-164.
 
14. Farrokhi, E., Samani, K.G., Chaleshtori, M.H. Oxidized low-density lipoprotein increases bone sialoprotein expression in vascular smooth muscle cells via runt-related transcription factor 2 (2015) American Journal of the Medical Sciences, 349 (3), pp. 240-243.
 
15. Ghatreh Samani, K., Farrokhi, E., Mohandes Samani, N. Elaidic acid effects on osteonectin gene expression in vascular smooth muscle cells (2015) Journal of Zanjan University of Medical Sciences and Health Services, 23 (97), pp. 103-111.
 
16. Ghanavati, T., Ghatreh-Samani, K., Farrokhi, E., Heydarian, E., Nikookar, M.
Effect of gallic acid on Alkaline phosphatase gene expression in vascular smooth muscle cells (2015) Journal of Mazandaran University of Medical Sciences, 25 (129), pp. 17-25.
 
17. Saneipour, M., Ghatreh-Samani, K., Heydarian, E., Farrokhi, E., Abdian, N.
Adiponectin inhibits oxidized low density lipoprotein-induced increase in matrix metalloproteinase 9 expression in vascular smooth muscle cells (2015) ARYA Atherosclerosis, 11 (3), 5 p.
 
18. Farrokhi, E., Samani, K.G., Chaleshtori, M.H. Oxidized low-density lipoprotein and upregulated expression of osteonectin and bone sialoprotein in vascular smooth muscle cells (2014) Laboratory Medicine, 45 (4), pp. 297-301.
 
19. Niknam, S., Samani, K.G., Amini, S.A., Farokhi, E.
Adiponectin effects on osteonectin gene expression in vascular smooth muscle cell line
(2014) Journal of Mazandaran University of Medical Sciences, 24 (109), pp. 216-222.
 
20. Saneipour, M., Samani, K.G., Heydarian, E., Farrokhi, E. The effect of adiponectin on matrix metalloproteinase-9 (MMP-9) in vascular smooth muscle cells (2014) Journal of Kerman University of Medical Sciences, 21 (5), pp. 384-393.
 
21. Jafari, A., Reiisi, S., Parchami, S., Ghatreh, K., Amiri, N., Miraj, S.The association of serum levels of folic acid and homocysteine in pregnant women with Pre-Eclampsia (2014) Iranian Journal of Obstetrics, Gynecology and Infertility, 17 (104), pp. 11-17.
 
22. Banitalebi, E., Gharakhanlou, R., Ghatrehsamani, K., Parnow, A.H., Teimori, H., Mohammad Amoli, M. The study of effect of resistance training on plasma SIP level and gene expression of S1P1,2,3 receptors in male Wistar rat (2013) Minerva Endocrinologica, 38 (4), pp. 395-400.
 
23. Heidarian, E., Movahed-Mohammadi, G., Saffari, J., Ghatreh-Samani, K.
Protective effect of hydroethanolic extract of cress against hepatotoxicity due to acetaminophen in rats (2013) Journal of Mazandaran University of Medical Sciences, 23 (102), pp. 78-90.
 
24. Moradi, M.-T., Gatreh-Samani, K., Farrokhi, E., Rafieian-Koupaei, M., Karimi, A. The effects of purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients (2012) Life Science Journal, 9 (4), pp. 5548-5552.
 
25. Samani, K.G., Farrokhi, E., Chaleshtory, M.H., Azadegan, F. Paraoxonase-1 L55M polymorphism with fatty acid composition of phospholipids in high-density lipoproteins (2012) Tehran University Medical Journal, 70 (1), pp. 7-14.
 
26. Setorki, M., Rafieian, M., Heidarian, E., Ghatreh, K., Shahinfard, N., Ansari, R., Forouzandeh, Z. Effect of rhus coriaria consumption with high cholesterol food on some atherosclerosis risk factors in rabbit (2012) Journal of Babol University of Medical Sciences, 14 (3), pp. 38-45.
 
27. Setorki, M., Rafieian Kopaei, M., Heidarian, E., Ghatreh, K., Shahinfard, N., Ansari, R., Frozandeh, Z. The beneficial effects of Vaccinium myrtilus L. intake on atherosclerosis risk factors in male New Zealand rabbits (2012) Journal of Zanjan University of Medical Sciences and Health Services, 20 (79), .
 
28. Ghatreh Samani, K., Noori, M., Rohbani Nobar, M., Hashemzadeh Chaleshtory, M., Farrokhi, E., Darabi Amin, M. The -514C/T polymorphism of hepatic lipase gene among iranian patients with coronary heart Disease (2012) Iranian Journal of Public Health, 41 (1), pp. 59-65.
 
29. Farrokhi, E., Shayesteh, F., Asadi Mobarakeh, S., Roghani Dehkordi, F., Ghatreh Samani, K., Hashemzadeh Chaleshtori, M. Molecular characterization of iranian patients with possible familial hypercholesterolemia (2011) Indian Journal of Clinical Biochemistry, 26 (3), pp. 244-248.
 
30. Darabi, M., Abolfathi, A.A., Noori, M., Kazemi, A., Ostadrahimi, A., Rahimipour, A., Darabi, M., Ghatrehsamani, K. Cholesteryl ester transfer protein I405V polymorphism influences apolipoprotein A-I response to a change in dietary fatty acid composition. (2009) Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, 41 (7), pp. 554-558.
 
31. Samani, K.G., Noori, M., Nobar, M.R., Chaleshtori, M.H., Farrokhi, E., Amin, M.D. I405V and -629C/A polymorphisms of the cholesteryl ester transfer protein gene in patients with coronary artery disease (2009) Iranian Biomedical Journal, 13 (2), pp. 103-108.
 
32. Noori, M., Darabi, M., Rahimipour, A., Rahbani, M., Abadi, N.A., Darabi, M., Ghatrehsamani, K. Fatty acid composition of HDL phospholipids and coronary artery disease (2009) Journal of Clinical Lipidology, 3 (1), pp. 39-44.
 
33. Ghatrehsamani, K., Darabi, M., Rahbani, M., Hashemzadeh Chaleshtory, M., Farrokhi, E., Noori, M. Combined hepatic lipase -514C/T and cholesteryl ester transfer protein I405V polymorphisms are associated with the risk of coronary artery disease.
(2009) Genetic testing and molecular biomarkers, 13 (6), pp. 809-815.
 
34. Hashemzadeh Chaleshtori, M., Farhud, D.D., Crosby, A.H., Farrokhi, E., Pour Jafari, H., Ghatreh Samani, K., Safa Chaleshtori, K., Kasiri, M., Shahrani, M., Mobini, G.R., Banitalebi, M., Mansouri, M., Modarresinia, D., Jafari, M. Molecular pathology of 6 novel GJB2 allelic variants detected in familial and sporadic Iranian non syndromic hearing loss cases (2008) Iranian Journal of Public Health, 37 (3), pp. 9-18.
 
35. Chaleshtori, M.H., Farrokhi, E., Shahrani, M., Kheiri, S., Dolati, M., Rad, L.H., Pour-Jafari, H., Samani, K.G., Chaleshtori, K.S., Crosby, A.H. High carrier frequency of the GJB2 mutation (35delG) in the north of Iran (2007) International Journal of Pediatric Otorhinolaryngology, 71 (6), pp. 863-867.

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