Saccharum officinarum L. sugarcane, is a large, strong-growing species of grass in the genus Saccharum. It originated in Southeast Asia and is now cultivated in tropical and subtropical countries worldwide for the production of sugar and other products. S. Officinarum, a perennial plant, grows in clumps consisting of a number of strong unbranched stems.The aim of this study is to overview its therapeutic effects than its nutritive and industrial effects. This review article was carried out by searching studies in PubMed, Medline, , Web of Science, and Iran Medex databases up to 2016.totally, of 112 found articles,40 articles(42 in vitro and 5 animal studies) were included. The search terms were “Saccharum officinarum L.”, “therapeutic”, “and pharmacological”. Various studies have shown that elder flower (Sambucus nigra). Possess Antioxidant activity, Immunotherapeutic effects, Anti-inflammation effects, Hepatotoxicity, Anti-obesity effects, Anti-malaria effects .elderflower (Sambucus
nigra) is widely used for therapeutic and purposes that trigger its significant value. Various combinations and numerous medicinal properties of its extract, essential oils, its stems and leaves demand further and more studies about the other useful and unknown properties of this multipurpose plant.